通过基于雷利波模型的光学连贯弹性学对人类镜头和镜头囊弹性的定量评估
Gang Shi1,2, Yubao Zhang2, Yidi Wang2
1School of Mathematics and Physics, University of Science and Technology Beijing, Beijing, China.
Journal of biophotonics
|October 17, 2024
概括
光学连贯弹性图 (OCE) 揭示了人眼透镜和囊的与年龄相关的硬化. 随着年龄的增长,镜头变得比其囊更为硬,为与年龄相关的视力变化提供了洞察力.
科学领域:
- 眼科医生 眼科 眼科
- 生物医学工程 生物医学工程
- 材料科学 材料科学 材料科学
背景情况:
- 眼睛的透镜和囊与年龄相关的变化会影响视力,影响白内障和长视等疾病.
- 了解这些组织的生物力学特性对于诊断和治疗策略至关重要.
研究的目的:
- 开发和应用光学连贯弹性图 (OCE) 技术来评估人体透镜和透镜囊弹性.
- 量化镜头和镜头囊的生物机械性能与年龄相关的变化.
主要方法:
- 开发一种新的光学连贯弹性成形技术.
- 在体内评估不同年龄组的人类透镜和透镜囊的弹性 (Young的模量).
主要成果:
- 随着年龄的增长,镜片的平均模量从12.28 ± 0.87 kPa增加到18.59 ± 1.45 kPa.
- 随着年龄的增长,镜头囊的平均模量从6.33 ± 0.36 kPa增加到13.33 ± 0.74 kPa.
- 镜头弹性始终高于镜头囊弹性,两者都随着年龄的增长而显著增加.
结论:
- 通过OCE技术,成功评估了人体透镜和透镜囊的弹性.
- 与年龄相关的透镜和透镜囊的硬化得到了定量证明.
- 这种技术显示出作为研究透镜相关疾病和衰老的临床工具的潜力.
更多相关视频
相关概念视频
Strain and Elastic Modulus
3.5K
The quantity that describes the deformation of a body under stress is known as strain. Strain is given as a fractional change in either length, volume, or geometry under tensile, volume (also known as bulk), or shear stress, respectively, and is a dimensionless quantity. The strain experienced by a body under tensile or compressive stress is called tensile or compressive strain, respectively. In contrast, the strain experienced under bulk stress and shear stress is known as volume and shear...
3.5K
Relation between Poisson's ratio, Modulus of Elasticity and Modulus of Rigidity
252
Deformation occurs in axial and transverse directions when an axial load is applied to a slender bar. This deformation impacts the cubic element within the bar, transforming it into either a rectangular parallelepiped or a rhombus, contingent on its orientation. This transformation process induces shearing strain. Axial loading elicits both shearing and normal strains. Applying an axial load instigates equal normal and shearing stresses on elements oriented at a 45° angle to the load axis.
252
Elastic Strain Energy for Shearing Stresses
165
As discussed in previous lessons, strain energy in a material is the energy stored when it is elastically deformed, a concept crucial in materials science and mechanical engineering. This energy results from the internal work done against the cohesive forces within the material. When a material undergoes shearing stress and corresponding shearing strain, the strain energy density, which is the energy stored per unit volume, is calculated. Within the elastic limit, where the stress is...
165
Elastic Strain Energy for Normal Stresses
142
Strain energy quantifies the energy stored within a material due to deformation under loading conditions, a fundamental concept in materials science and engineering. The strain energy can be modeled when a material is subjected to axial loading with uniformly distributed stress. In this scenario, the stress experienced by the material is the internal force divided by the cross-sectional area, and the strain induced is directly proportional to this stress through the modulus of elasticity.
If...
If...
142
Elasticity
3.4K
Elasticity is the ability of an object to withstand the effects of distortion and to return to its original size and shape once the forces causing deformation are removed. When an elastic material deforms under the action of an external force, it experiences internal resistance to the deformation. However, if no external force is applied, it returns to its original state.
The elasticity of an object can be described by a stress-strain curve, which represents the relationship between stress...
The elasticity of an object can be described by a stress-strain curve, which represents the relationship between stress...
3.4K
Hooke's Law
351
Hooke's law, a pivotal principle in material science, establishes that the strain a material undergoes is directly proportional to the applied stress, defined by a factor called the modulus of elasticity or Young's modulus.
351


