肺高血压和右心室功能障碍对接受米特拉置换术的患者早期死亡率和发病率的影响
Faruk Gencoglu1, Mehmet Ali Yesiltas2, Ozan Koyuncu3
1Department of Cardiovascular Surgery, Hisar Intercontinental Hospital, Istanbul, Turkey.
BMC cardiovascular disorders
|October 17, 2024
概括
在米特拉置换患者中,严重的肺高血压和低TAPSE增加了早期死亡率和发病率. 在肺压力上升之前进行早期的手术干预对于在中枢疾病中获得更好的生存结果至关重要.
科学领域:
- 心脏病学 心脏病学
- 心脏外科手术 心脏外科手术
- 肺高血压是什么意思 肺高血压
背景情况:
- 同时进行三管门手术很少适用于类风湿性 mitra 门手术.
- 严重的肺高血压和低三环状平面缩外流 (TAPSE) 可能会影响米特拉置换 (MVR) 的结果.
研究的目的:
- 研究重症肺高血压和低TAPSE对接受MVR的患者的早期死亡率和发病率的影响.
- 确定MVR患者肺动脉压升高 (PAP) 的不良结果的危险因素.
主要方法:
- 对MVR患者的回顾性分析 (2013年1月 - 2020年8月).
- 根据肺动脉压分类的患者 (PAP ≥50 mmHg与<50 mmHg).
- 基于TAPSE (≥1.5毫米与<1.5毫米) 的高PAP组内的子组分析.
- 两组之间的早期死亡率和发病率的比较.
主要成果:
- 79名患者 (68%为女性) 接受了MVR.
- 53名患者的PAP>50 mmHg;26名患者的PAP<50 mmHg.
- 高PAP组显示出显著更高的三腹吐率,输血,ICU停留,需要CPAP,再输管,急性功能衰竭和死亡率 (p<0.05对所有人).
结论:
- 在MVR患者中,肺动脉压升高与早期死亡率和发病率的增加有关.
- 在肺压力显著增加和右心室功能障碍发生之前,建议对心心病理进行早期手术干预.
- 及时治疗可以提高患有 mitra 病和肺高血压的患者的生存结果.
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