在宫癌发生过程中,HPV16集成通过c-Myc/miR-142-5p/HOXA5/SLC7A11轴调节铁灭菌耐药性

Xiao-Jing Chen1,2, Chu-Hong Guo1, Yang Yang1,3

  • 1Department of Obstetrics and Gynecology, The First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, Yuexiu District, Guangzhou, 510120, People's Republic of China.

Cell & bioscience
|October 18, 2024
PubMed
概括

高风险的HPV16集成通过激活c-Myc/miR-142-5p/HOXA5/SLC7A11通路,促进子宫癌中的铁灭抵抗. 这一发现为HPV16相关的宫平细胞癌提供了潜在的治疗策略.

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