患有前性痴呆症的个体的认知储备:系统性审查
Lauren A Grebe1,2,3, Jet M J Vonk3, Elizabeth E Galletta4,5
1Communication Sciences and Disorders, St. John's University, Queens, NY, USA.
Journal of clinical and experimental neuropsychology
|October 18, 2024
概括
在使用教育,职业和休代理时,认知储备 (CR) 在前性痴呆症 (FTD) 中显示部分支持. 在FTD研究中,发现的变化可能来自于CR,大脑状态和疾病严重程度的各种测量工具.
科学领域:
- 神经科学是一个神经科学.
- 神经学 神经学
- 认知科学 认知科学
背景情况:
- 正在出现关于前性痴呆症 (FTD) 认知储备 (CR) 的文献,缺乏关于CR代理,大脑状态和临床性能关系的共识.
- 了解这些关系对于FTD患者的管理和研究至关重要.
研究的目的:
- 系统地审查FTD患者的社会行为CR代理,大脑状态和临床表现之间的关系.
- 在现有的FTD研究中识别患者群体的特征,CR代理,疾病严重程度工具和大脑状况措施.
主要方法:
- 通过使用Medline,PsychINFO,PubMed和Web of Science进行了系统性审查.
- 包括的研究要求FTD患者至少有一个CR和一个大脑状况测量,同行评审的英语出版.
- 研究质量和偏差风险使用纽卡斯尔-太华质量评估尺度进行评估.
主要成果:
- 报告了1423名FTD参与者的13项研究符合纳入标准.
- 当使用教育,职业和休作为代理时,在FTD中发现了部分支持CR.
- 结果的变化可能归因于CR,大脑状态和疾病严重程度的各种测量工具.
结论:
- 对未来FTD研究的建议包括纵向设计,全面的神经心理测试,标准化疾病持续时间测量和透明的统计报告.
- 需要进一步的研究来澄清认知储备在前性痴呆症中的作用.
- 标准化的方法对于推动FTD研究和理解认知储备至关重要.
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