一个病例报告的psilocybin诱导的精神病在一个有倾向的患者
1Mental Health Service, San Francisco VA Health Care System, San Francisco, CA, USA.
概括
魔术中的一种化合物psilocybin显示出对心理健康的承诺,但也带来了风险. 这一案例突显了在具有易感因素的个体中,即使在低剂量中,也引起了psilocybin的精神病.
科学领域:
- 精神病学是一个精神病学.
- 神经科学是一个神经科学.
- 药理学 药理学是指药理学的学科.
背景情况:
- псилоцибин对焦虑和抑郁症等心理健康状况具有治疗潜力.
- 患有精神病风险因素的个体通常被排除在临床试验之外.
- 在现实世界中,使用psilocybin可能涉及患有并发症和精神病倾向的个体.
研究的目的:
- 在患有多种风险因素的患者中报告一例psilocybin诱导的精神病.
- 审查现有的关于弱势群体中 псилоцибин诱导精神病的文献.
- 告知研究人员和临床医生关于与西使用相关的潜在风险.
主要方法:
- 一个患有抑郁症,人格障碍特征和大麻使用的患者的病例报告.
- 详细描述了患者的精神病发作,在使用psilocybin后出现了catatonia和自杀倾向.
- 文献综述以前发表的关于西诱导精神病的病例报告.
主要成果:
- 患者经历了一次精神病发作,在长期,重量使用psilocybin后出现了触动性特征和自杀倾向.
- 从病例报告中出现了一个模式:psilocybin诱导的精神病主要影响使用高剂量或重复剂量的易感因素的个体.
- 这份案例报告与观察到的模式保持一致,并加强了这种模式.
结论:
- 西的使用与风险有关,特别是对于患有精神病倾向因素的人来说.
- 高剂量或重复服用西可能会在易受伤害的个体中引发精神病发作.
- 这些发现为使用 псилоцибин提供了警告,并为受控的低剂量研究提供了保证.
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