机构措施对静脉注射免疫球蛋白最佳使用的影响
Jean-Nicolas Champagne1, Antoine Desilets2, Guillaume Roy1
1Université de Montréal, Montreal, Quebec, Canada.
Transfusion
|October 18, 2024
概括
实施机构措施显著减少了静脉注射免疫球蛋白 (IVIG) 的使用,特别是在不推的适用症方面. 这项研究强调了优化IVIG利用在短缺的情况下的有效策略.
科学领域:
- 输血医学 输血医学
- 免疫学 免疫学 免疫学
- 药物经济学 药物经济学
背景情况:
- 静脉注射免疫球蛋白 (IVIG) 短缺在输血医学中构成了越来越大的挑战.
- 关于优化IVIG使用的有效策略的数据有限.
- 本研究评估了机构措施对学术中心IVIG消费的影响.
研究的目的:
- 评估实施的机构战略在管理IVIG利用方面的有效性.
- 分析限制措施后IVIG适宜性和总体消费的变化.
主要方法:
- 追溯观察性研究分析了2018年11月至2022年9月期间的5431次IVIG输液.
- 根据省级指南,根据适当性 (推,可选,不推) 分类输液.
- 数据在三个阶段进行分析:参考,过渡和后实施 (限制性措施之后).
主要成果:
- 总体而言,IVIG输液减少了23.0%,不推的适应症从9.5%降至7.4%.
- 超过推剂量的订单显著减少 (20.8%至3.9%).
- 不推和过量的IVIG剂量从15.2%降至6.6%的总用克.
结论:
- 一套全面的限制性策略,包括标准化表格和管理,有效地减少了IVIG的整体使用.
- 实施的措施优先减少了不推和过度的IVIG订单.
- 这些发现表明,在短缺期间管理IVIG资源的成功方法.
相关概念视频
Routes of Drug Administration: Parenteral
1.9K
The administration of drugs via parenteral routes allows for direct drug introduction into the systemic circulation, resulting in high bioavailability because the medication bypasses the harsh conditions of the gastrointestinal tract and hepatic metabolism.
The intravenous route (IV) of drug administration can be further categorized into two types. The bolus injection administers the entire dose rapidly, while an intravenous infusion slowly delivers smaller doses steadily.
The IV route is often...
The intravenous route (IV) of drug administration can be further categorized into two types. The bolus injection administers the entire dose rapidly, while an intravenous infusion slowly delivers smaller doses steadily.
The IV route is often...
1.9K
One-Compartment Model: IV Infusion
167
Intravenous (IV) infusion is often utilized when continuous and controlled drug delivery is necessary, such as during surgery or in the treatment of chronic diseases. This method offers numerous advantages, including immediate drug action, precise control over dosage, and bypassing the first-pass metabolism.
The one-compartment model for IV infusion uses mathematical equations to describe the rate of change in drug quantity in the body. At steady-state or infusion equilibrium, the drug input...
The one-compartment model for IV infusion uses mathematical equations to describe the rate of change in drug quantity in the body. At steady-state or infusion equilibrium, the drug input...
167
Healthcare Associated Infections II: Preventive Measures
2.5K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.5K
Venous Thrombosis III: Interprofessional Care
3
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
3


