人工智能应用用于抗瘤药物协同效应预测
Zheng Peng1, Yanling Ding2, Pengfei Zhang3
1Department of Clinical Laboratory, Liuzhou Traditional Chinese Medical Hospital, Liuzhou, Guangxi, China.
Current medicinal chemistry
|October 18, 2024
概括
使用人工智能 (AI) 预测协同作用的抗癌药物组合对于克服耐药性和改善患者治疗结果至关重要. 本综述探讨了人工智能应用在预测药物协同作用,以获得更有效的癌症疗法.
科学领域:
- 在瘤学瘤学.
- 计算生物学 计算生物学
- 药理学 药理学是指药理学的学科.
背景情况:
- 化疗对于癌症治疗至关重要,但面临着药物耐药性和有毒副作用等挑战.
- 单一药物治疗可能会导致耐药性,需要组合疗法以提高疗效.
- 开发有效的多药组合是复杂的,因为复杂的瘤生物学和药物相互作用.
研究的目的:
- 提供癌症药物协同疗法的全面概述.
- 探索人工智能 (AI) 在预测抗癌药物协同作用中的应用.
- 讨论深度学习在这个领域的挑战和未来前景.
主要方法:
- 审查有关癌症药物协同作用的现有文献.
- 分析人工智能 (AI) 技术,特别是深度学习,用于协同预测.
- 讨论用于识别协同作用药物组合的计算方法.
主要成果:
- 人工智能,特别是深度学习,在更准确,更高效地预测抗癌药物协同作用方面表现有前途.
- 人工智能可以帮助识别多种药物组合,克服耐药性并减少毒性.
- 对药物协同作用的系统选方法仍在开发中.
结论:
- 人工智能驱动的协同预测可以显著提升癌症治疗策略.
- 在药物协同作用中应用AI可以导致更有效的治疗计划和优化药物使用.
- 需要对深度学习方法进行进一步的研究,以应对当前的挑战并释放充分的潜力.
相关概念视频
02:50Combination Therapies and Personalized Medicine
4.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.9K
02:57Targeted Cancer Therapies
7.5K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.5K
01:27Tumor Immunotherapy
488
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
488