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Updated: Jun 10, 2025

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在药物与药物相互作用中,Everolimus诱导的ABCB1下调的参与

Yuko Nakayama1, Aya Ino2, Kazuhiro Yamamoto3

  • 1Department of Clinical Pharmaceutics, Faculty of Pharmaceutical Sciences, Himeji Dokkyo University, Himeji 670-8524, Japan.

Biomedical reports
|October 18, 2024
PubMed
概括

持续暴露于mTOR抑制剂everolimus,抑制了肠道的ABCB1和ABCG2运输体. 这一发现表明,在长期癌症治疗期间,潜在的药物相互作用会影响口服生物可用性.

关键词:
在ABCB1中,ABCB1是ABCB1.在Caco-2细胞中.下调调节的下调调节方法药物相互作用 药物相互作用这是Everolimus.运输商 运输商 运输商 运输商

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