拉丁美洲乳头甲状腺癌的积极监测:一个范围审查
Pedro Garnier Manfio1, Lucas Albuquerque Chinelatto2, Flávio Carneiro Hojaij3
1Universidade de São Paulo Faculdade de Medicina São PauloSP Brasil Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil.
Archives of endocrinology and metabolism
|October 18, 2024
概括
积极监测 (AS) 是拉丁美洲低风险乳头甲状腺小癌 (PTMCs) 的安全有效策略. 虽然焦虑会导致中断,但结果是有利的,支持AS作为一种可接受的方法.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 甲状腺结节很常见,有7%-15%的恶性瘤. 一些恶性结节是惰的,可能不会影响死亡率.
- 积极监测 (AS) 提供了一种策略,以避免对乳头甲状腺小癌 (PTMCs) 的过度治疗.
研究的目的:
- 评估拉丁美洲低风险PTMC的AS当前状态.
- 确定该地区与AS相关的文化,后勤和财务挑战.
- 分析AS接受PTMC患者的疾病进展数据和结果.
主要方法:
- 2014年以后发表的关于拉丁美洲成年患者的研究的系统审查.
- 在PubMed (MEDLINE),SciELO,LILACS和科学网上进行的搜索.
- 分析AS协议,挑战,坚持,中断原因,手术转换,持续时间和疾病进展.
主要成果:
- 包括三项研究,所有这些研究都认为AS是可行的,结果与国际数据相似.
- 瘤进展和结果是有利的;没有新的远程转移报告.
- 焦虑是AS中断的主要原因;用于随访的部超声波和特定的血液标记物 (TSH,T4,甲状腺蛋白,抗甲状腺蛋白抗体).
结论:
- 积极监测是拉丁美洲低风险PTMC的可接受,安全和有效方法.
- 需要进一步的前性研究来巩固该地区的AS.
- 成功的AS需要适当的基础设施,多学科的团队,患者教育和强大的后续协议.
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