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截断的4'-氨基核酸的结构-活性关系:腺素受体活性和结合选择性

Minjae Kim1, Hongseok Choi1, Akshata Nayak2

  • 1Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Korea.

ACS medicinal chemistry letters
|October 18, 2024
PubMed
概括

截断的4'-氨基核化物对A3腺受体 (AR) 具有选择性结合. 化合物6l和6m是强大的配体,6m作为部分激动剂,提供新的治疗潜力.

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