评估心力衰竭患者修改H2FPEF评分的预后值,使用保存的喷射分数
Ya Qiong Jin1, Lu Geng1, Yue Li1
1Department of Cardiology, The Second Hospital of Hebei Medical University, Shijiazhuang City, Hebei 050000, China.
Cardiology research
|October 18, 2024
概括
经过修改的H2FPEF评分,使用较低的肥胖BMI值,更好地预测中国心力衰竭患者的心血管事件. 超过6.5的分数表明风险增加.
科学领域:
- 心脏病学 心脏病学
- 医学诊断 医学诊断 医学诊断
- 公共卫生 公共卫生
背景情况:
- H2FPEF评分是一个用于诊断心力衰竭的工具,具有保存的喷射分数 (HFpEF).
- 它在中国HFpEF患者的预后效用需要进一步验证.
- 这项研究评估了该人群中修改后的H2FPEF得分.
研究的目的:
- 评估中国HFpEF患者修改的H2FPEF评分的预后价值.
- 为了比较修改后的得分与原来的H2FPEF得分的预测能力.
- 确定不良心血管事件的风险值.
主要方法:
- 对497名中国HFpEF患者进行了回顾性研究.
- 使用BMI值≥25 kg/m2 (修改) 和≥30 kg/m2的H2FPEF得分进行计算.
- 在平均随访时间为40.46个月的时间内,评估了与HF相关的事件和急性冠状动脉综合征 (ACS).
- 使用考克斯模型和ROC曲线进行分析.
主要成果:
- 更高的修改H2FPEF得分与增加的HF相关事件和ACS相关.
- 与原始得分相比,修改后的得分 (BMI ≥25 kg/m2) 显示HF事件 (AUC: 0.723) 和ACS (AUC: 0.670) 的预测优于原始得分.
- 截止分数为6.5有效预测了不良结果.
结论:
- 修改后的H2FPEF评分,通过BMI ≥25 kg/m2来定义肥胖,是中国HFpEF患者心血管事件的更有效预测指标.
- 修改后H2FPEF得分超过6.5是该人群中不良心血管事件的重要危险因素.
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