用身体活动和睡眠取代久坐不动行为对中风风险的影响:一项前性队列研究
Xiao-Fang Dong1, Qiang Zhang2, Jia-Ning Wei2
1Department of Endocrinology and Metabolic Diseases, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Nature and science of sleep
|October 18, 2024
概括
减少久坐不动行为和改善睡眠是降低中风风险的关键. 将休时间的SB替换为体育活动或睡眠显著降低了中风的发生率,特别是在那些有不健康睡眠模式的人群中.
科学领域:
- 神经学 神经学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 久坐不动的行为 (SB) 越来越被认为是一个重大的公共卫生问题.
- 了解休时间SB,睡眠和中风风险之间的关系对于预防策略至关重要.
研究的目的:
- 调查休时间的久坐行为 (SB) 与中风风险之间的相关性.
- 分析用同位 temporal 替代模型 (ISM) 用轻度体力活动 (LPA),中度体力活动 (MPA),剧烈体力活动 (VPA) 或睡眠替换SB对中风风险的影响.
主要方法:
- 利用了英国生物银行478,198名参与者的数据.
- 通过标准化问卷收集休时间SB和体力活动 (PA) 数据.
- 采用了考克斯的比例危险和同时代替代模型 (ISM) 进行分析.
主要成果:
- 在12.7年的时间里,确定了10003起中风病例.
- 随着漫长的休时间SB (HRs从1.06到1.24为>4小时/天) 观察到中风风险增加.
- 用LPA,VPA或睡眠取代休时间的SB,可以显著降低中风风险 (在每天8小时以上睡眠的个体中,睡眠替代的风险高达22.0%).
结论:
- 休时间的SB和不健康的睡眠时间是确定的中风风险因素.
- 用充足的睡眠或VPA取代SB是一种有效的中风风险降低策略,特别是对于特定睡眠时间的人来说.
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