尼日利亚深层真菌病的皮肤表现:系统审查
Thelma E Bassey1, Ikechukwu Okekemba2, Walter O Egbara1
1Department of Internal Medicine, University of Calabar Teaching Hospital, Calabar, Nigeria.
Therapeutic advances in infectious disease
|October 18, 2024
概括
在尼日利亚,与皮肤相关的深层菌根病例报告不足,其中基因质和eumycetoma是常见的. 报告的减少表明需要增加临床怀疑和及时组织学诊断.
科学领域:
- 菌类学 菌类学是指菌类学.
- 皮肤病学 皮肤病学
- 传染性疾病 传染性疾病
背景情况:
- 深层真菌病是一种严重的真菌感染,影响免疫力低下和免疫能力强的人.
- 皮肤表现在深层真菌菌中很常见,特别是在菌病原体暴露率高的地区.
- 尼日利亚关于皮肤参与的深层真菌菌的文献有限.
研究的目的:
- 在尼日利亚系统地审查临床表现,风险因素和皮肤表现的深层真菌病的诊断.
- 随着时间的推移,确定报告和诊断这些感染的趋势.
主要方法:
- 按照PRISMA指南进行系统审查.
- 搜索了PubMed,谷歌学者和非洲期刊在线数据库 (从开始到2024年2月).
- 包括尼日利亚皮肤深层真菌感染的病例报告和系列;不包括评论,元分析和非尼日利亚研究.
主要成果:
- 确定了16篇文章,详细介绍了尼日利亚六十年来137例深皮真菌病例.
- 组织等离子体 (63.5%) 和囊瘤 (13.9%) 是最常见的诊断.
- 主要的危险因素包括农业 (9.5%) 和糖尿病 (2.2%).
- 诊断主要是通过组织病理学 (95.6%);15.3%最初被误诊为癌症或其他疾病.
结论:
- 报告病例的减少表明潜在的诊断不足或临床怀疑低.
- 错误诊断和其他疾病凸显了诊断方面的挑战.
- 强调皮肤病变的组织学确认对于准确的诊断和管理至关重要.
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