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Updated: Jun 10, 2025

Preparation of 3D Decellularized Matrices from Fetal Mouse Skeletal Muscle for Cell Culture
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Published on: March 3, 2023

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心肌细胞中的拉特罗菲林-2 删除会破坏细胞结合,导致D-CMP

Minjun Kang1,2, Choon-Soo Lee1,2, HyunJu Son1,2

  • 1Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, College of Medicine or College of Pharmacy, Seoul National University, South Korea (M.K., C.-S.L., H.S., H.J.S., H.-S.K.).

Circulation research
|October 18, 2024
PubMed
概括

拉特罗菲林-2 (Lphn2) 对于成人心脏完整性至关重要,控制线粒体功能和细胞结合. 它的缺失导致扩张性心肌病,但p38-MAPK通路激活剂可以恢复心脏功能.

关键词:
心肌病,扩张心肌病,扩张心肌病.死亡,突然死亡,突然的死亡.线粒体中的线粒体.心肌梗塞的心脏病发作

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High-Throughput Cardiotoxicity Screening Using Mature Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Monolayers14:03

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