在患有慢性炎症性风湿性疾病的患者中,中央敏感化的患病率和相关因素
Imane Berrichi1, Fatima Zahrae Taik1, Fouzia Haddani1
1Rheumatology Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Abdelmalek Essaadi University, Tangier.
Current rheumatology reviews
|October 18, 2024
概括
中枢敏感性 (CS) 影响了近一半的慢性炎症性风湿性疾病 (CIRD) 患者. 疼痛严重程度和抑郁症是与CIRD患者的CS相关的关键因素,突出了综合治疗方法的必要性.
科学领域:
- 类风湿病学 类风湿病学
- 疼痛医学 医学 疼痛医学
- 精神病学是一个精神病学.
背景情况:
- 慢性炎症性风湿性疾病 (CIRD) 显著影响患者的生活质量,尽管治疗进展,但疼痛仍然是一个持续的挑战.
- 中枢敏感性 (CS) 越来越多地被认为是各种慢性疾病 (包括CIRD) 中疼痛的促成因素.
研究的目的:
- 调查诊断为慢性炎症性风湿性疾病 (CIRD) 的患者中中央敏感化 (CS) 的流行情况.
- 确定与该患者群体中中央敏感性相关的社会人口统计学和临床因素.
主要方法:
- 在坦吉尔大学医院中心对189名CIRD患者进行了横截面研究.
- 收集的数据包括社会人口统计信息,疾病活动 (DAS-28,ASDAS),疼痛严重程度 (视觉模拟尺度 - VAS),CS (中央敏感化库存部分A - CSI-A),疼痛灾难化 (PCS) 和抑郁症 (PHQ-9).
主要成果:
- 在189名CIRD患者中,近一半 (44.9%) 的患者表现出中央敏感化库存得分为40或更高.
- 中心敏感性与更高的疼痛严重程度 (VAS) 和抑郁症状的存在 (PHQ-9) 有关.
- 在CSI-A得分和疼痛VAS之间观察到统计学上显著的相关性 (r = 0.32,p < 0.001).
结论:
- 在患有慢性炎症性风湿性疾病的患者中,中央敏感性非常普遍.
- 疼痛严重程度和抑郁症是导致CIRD患者中枢敏感性的重要因素.
- 这些发现强调了在管理CIRD时解决心理因素和疼痛感知的重要性.
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