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Updated: Jun 10, 2025

Optogenetic Phase Transition of TDP-43 in Spinal Motor Neurons of Zebrafish Larvae
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Optogenetic Phase Transition of TDP-43 in Spinal Motor Neurons of Zebrafish Larvae

Published on: February 25, 2022

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RNA结合蛋白功能障碍将燃烧/缓慢扩张的病变与多发性硬化症中神经退行症联系起来

Miranda L Messmer1,2,3, Hannah E Salapa1,2,4, Bogdan F Popescu2,3

  • 1Office of the Saskatchewan Multiple Sclerosis Clinical Research Chair, University of Saskatchewan, Saskatoon, SK, Canada.

Annals of neurology
|October 18, 2024
PubMed
概括

RNA结合蛋白 hnRNP A1 功能障碍有助于多发性硬化症 (MS) 中的神经退行,可能由缓慢扩展的病变 (SEL) 恶化. 这项研究揭示了对MS大脑中神经元损伤和疾病进展的见解.

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