相关实验视频

Updated: Jun 10, 2025

Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test OGTT and Insulin Tolerance Test ITT
08:13

Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test OGTT and Insulin Tolerance Test ITT

Published on: January 7, 2018

68.0K

种群特异的Thr44Met OCT3编码变体影响了甲福林的药理动力学,随后对C57Bl/6J小鼠的胰岛素敏感性产生影响

Qian Wang1,2, Megan P Leask3, Kate Lee1,2

  • 1Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand.

Diabetologia
|October 18, 2024
PubMed
概括

在SLC22A3基因 (rs8187715) 中的一种遗传变异增加了波利尼西亚人的甲福林摄入量. 虽然这种变体急剧改善了胰岛素敏感性,但它的长期益处在甲福林治疗上并没有得到增强.

关键词:
在 SLC22A3 中.糖尿病 糖尿病 糖尿病这是GDF-15的GDF-15.胰岛素敏感性的原因甲胺是一种甲胺.药物遗传学 药物遗传学精准医学是一门精准的医学.

更多相关视频

Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes08:30

Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes

Published on: March 15, 2018

14.1K
Body Composition and Metabolic Caging Analysis in High Fat Fed Mice10:28

Body Composition and Metabolic Caging Analysis in High Fat Fed Mice

Published on: May 24, 2018

15.4K

相关概念视频

Oral Hypoglycemic Agents: Biguanides and Glitazones01:26

Oral Hypoglycemic Agents: Biguanides and Glitazones

Biguanides, particularly metformin (Glucophage), are insulin sensitizers that enhance glucose uptake, thereby reducing insulin resistance. Unlike sulfonylureas, metformin doesn't prompt insulin secretion, which helps to curb hypoglycemia risk. Metformin is beneficial in treating conditions like polycystic ovary syndrome due to its insulin-resistance reduction capability. The drug's primary action involves curtailing hepatic gluconeogenesis, a significant contributor to high blood...
176
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
33.4K