内部血液瘤架构预测了体内血液瘤对独立中脑膜动脉栓塞的响应能力
Danielle Golub1, Joshua D McBriar2, Brianna M Donnelly2
1Department of Neurosurgery, Northwell Health, Manhasset, NY, USA. Dgolub1@northwell.edu.
Neuroradiology
|October 18, 2024
概括
独立的中脑膜动脉栓塞 (MMAE) 有效地治疗腹膜下血瘤 (SDH),特别是那些具有膜状内部结构的血液瘤. 这种微创手术的失败率和并发症率很低,为非急性SDH病例提供了持久的选择.
科学领域:
- 神经外科 神经外科
- 干预性放射学 干预性放射学
- 血管外科 血管外科
背景情况:
- 腹膜下血液瘤 (SDH) 是一种常见的神经外科疾病,特别是在老年人群中.
- 中脑膜动脉栓塞 (MMAE) 是一种新兴的SDH治疗方法,在与手术一起使用时可以减少复发.
- 成功独立MMAE的预测因素需要进一步定义.
研究的目的:
- 评估MMAE作为SDH独立治疗的疗效和安全性.
- 确定MMAE在SDH管理中的成功的临床和放射学预测因素.
- 评估SDH内部架构对MMAE结果的影响.
主要方法:
- 对于164个独立的MMAE病例进行一次性SDH治疗 (2020-2023年) 的回顾性审查.
- SDH内部架构的分类:均的,分离的,层状的或状的.
- 评估SDH厚度,复发,扩张和治疗失败的情况.
主要成果:
- 整体MMAE治疗失败率为6.7%,周围手术并发症率为4.9%.
- 状和层状SDH集合比同质和分离的集合大 (16.2毫米对14.2毫米).
- 在层状/状SDH (1.2%) 和均质/分离SDH (12.4%) 中,MMAE失败明显较低. 同质/分离的架构预测了MMAE失败 (OR 10.5).
结论:
- 独立MMAE是一种安全,有效和持久的治疗非急性SDH.
- SDH内部架构,特别是层状和状类型,与更好的MMAE结果有关.
- 同质和分离的SDH内部架构是MMAE失败和延迟再吸收的预测因素.
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