黑人女性表皮卵巢癌的饮食和生存率
Tsion A Armidie1, Elisa V Bandera2, Courtney E Johnson1
1Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia.
JAMA network open
|October 18, 2024
概括
饮食模式可能会影响黑人女性高度血清性卵巢癌 (HGSOC) 的生存率. 中等到高的预诊断饮食质量与这种脆弱人群的较低死亡率有关.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 营养科学 营养科学
背景情况:
- 卵巢癌的生存率在黑人女性中最低.
- 饮食不良不成比例地影响黑人人口,但其与卵巢癌存活率的联系还未得到充分研究.
研究的目的:
- 调查黑人妇女的饮食模式和存活率之间的关联,这些妇女被诊断出患有上皮卵巢癌 (EOC).
主要方法:
- 在非洲裔美国癌症流行病学研究 (AACES) 中对483名患有EOC的黑人妇女进行前性队列研究.
- 使用健康饮食指数-2020 (HEI-2020) 和基于预诊断摄入量的替代健康饮食指数-2010 (AHEI-2010) 评估的饮食模式.
- 使用多变量考克斯模型分析死亡率.
主要成果:
- 在所有EOC患者中,饮食模式和死亡率之间没有总体关联.
- 在325名患有高度血清性卵巢癌 (HGSOC) 的女性中,较高的HEI-2020和AHEI-2010得分与死亡率降低有关.
- 具体来说,HEI-2020的四分位数2-4和AHEI-2010的四分位数2和4的死亡率与第一四分位数相比显著降低.
结论:
- 中等到高的预诊断饮食质量与HGSOC的黑人妇女的死亡率明显降低有关.
- 这些发现凸显了饮食改善对这一特定患者群体生存的潜在益处.
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