交换系统和程序对ESKD患者经历CAPD的长期腹膜炎的影响:一项追溯比较队列研究
Phongsak Dandecha1, Atthaphong Phongphithakchai1
1Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand.
Iranian journal of kidney diseases
|October 18, 2024
概括
腹膜透析系统ANDY-Disc和DIANEAL显示了可比的长期腹膜炎率和技术存活率. 需要进一步进行高质量的试验,以在现实环境中证实这些发现.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 脏替代疗法治疗 脏替代疗法
- 腹膜透析是指腹膜透析.
背景情况:
- 腹腔透析 (PD) 通常使用双袋交换系统,包括ANDY-Disc和DIANEAL.
- 关于腹膜炎的发病率和这些系统的技术耐用性的长期结果尚未确立.
- 现实世界的数据对于了解不同PD交换系统的比较有效性至关重要.
研究的目的:
- 为了比较ANDY-Disc和DIANEAL交换系统之间的腹膜炎的长期发病率.
- 为了评估与每种系统相关的技术存活率,在持续的门诊腹膜透析 (CAPD) 患者中.
- 在现实临床环境中评估这些系统对腹膜炎发病率的影响.
主要方法:
- 一项回顾性比较队列研究包括了120名从2009年到2020年接受PD的患者.
- 患者使用ANDY-Disc或DIANEAL双袋交换系统进行治疗.
- 主要结局:腹膜炎发病率. 二次结果:致病生物,第一次腹膜炎的时间和技术生存率.
主要成果:
- 腹膜炎的发病率相似:ANDY-Disc的发病率为0.28次/患者年,DiANEAL的发病率为0.29次 (P = .816).
- 在这两组中,炎的最常见原因是阳性细菌.
- 10年技术的存活率显示了一个非显著的趋势,偏好ANDY-Disc (86.1%) 超过DIANEAL (73.5%).
结论:
- 在ANDY-Disc和DIANEAL系统中,长期腹膜炎的发病率相似.
- 两种PD交换系统都表现出类似的长期技术生存率.
- 建议进行高质量的临床试验来验证这些发现.
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