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一个创新的策略利用自我激活的CAR-NK细胞来缓解TGF-β1驱动的免疫抑制

Seung Hun Shin1, Young Eun Lee2, Han-Na Yoon3

  • 1Medicinal Materials Research Center, Biomedical Research Division, Korea Institute of Science and Technology, Seoul, Republic of Korea; Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea.

Biomaterials
|October 18, 2024
PubMed
概括

这项研究开发了新的仿真抗原受体 (CAR) -NK细胞,释放来阻止转化生长因子β1 (TGFβ1) 信号传递,增强对胰腺癌的抗瘤免疫力.

关键词:
化学抗原受体的化学抗原受体自然杀手细胞是什么?固体瘤是一个固体瘤.在TGFβ中,TGFβ是TGFβ.瘤微环境是一个微环境.

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