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Updated: Jul 10, 2026

Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients
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通过LC-MS/MS快速量化人类肺上皮层内膜液中的polymyxin B及其临床应用

Yu Wang1, Xiaofen Liu1, Yan Chen1

  • 1Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai 200040, China; Key Laboratory of Clinical Pharmacology of Antibiotics, National Health Commission of the People's Republic of China, Shanghai 200040, China.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
|October 18, 2024
PubMed
概括

一种新的液态色谱/双重质谱法准确地量化了支气管支气管洗液中的polymyxin B. 这使得吸入抗生素对肺部感染的药理动力学研究更好.

关键词:
人类肺上皮层内膜液.这是LC-MS/MS.肺炎患者中的肺炎患者.聚氨基 B 聚氨基 B 是一种

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Rapid Identification of Pathogens01:25

Rapid Identification of Pathogens

MALDI-TOF MS has transformed clinical microbiology by offering a rapid and reliable method for pathogen identification. The traditional approach to microbial identification typically involves time-consuming culture techniques and biochemical tests, which can delay the initiation of appropriate antimicrobial therapy. MALDI-TOF MS avoids these delays by using characteristic ribosomal protein mass patterns of microbial cells, enabling accurate species-level identification within minutes.Principle...