在细胞因子风暴综合征中DOCK8的作用

Mingce Zhang1, Remy R Cron1, Niansheng Chu2

  • 1University of Alabama at Birmingham, Birmingham, Ala.

概括

罕见的细胞动力学8 (DOCK8) 献体基因突变可能导致细胞因子风暴综合征 (CSSs). 缺少DOCK8会损害自然杀手 (NK) 细胞的功能,导致CSS患者的高炎症和器官衰竭.

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