在分娩后立即使用注射避孕药对乳糖生成的潜在影响
Maria F Gallo1, Fernanda L Schumacher1, Megan Lawley2
1The Ohio State University, College of Public Health, Columbus, OH, USA.
Contraception
|October 18, 2024
概括
在分娩后立即使用储存的美德基酸 (DMPA) 不会延迟乳腺发育第二阶段 (LS-II),也称为牛奶放下. 这一发现支持在哺乳期的母亲早期开始使用DMPA.
科学领域:
- 生殖健康 生殖健康
- 哺乳期生理学 哺乳期生理学
背景情况:
- 乳腺生成II阶段 (LS-II),或乳汁放下,对于建立母乳养至关重要.
- 德波特 (DMPA) 是一个常见的产后避孕选择.
- 立即产后DMPA对LS-II时间的影响需要澄清.
研究的目的:
- 评估马上产后使用美德酸 (DMPA) 对乳腺生成II阶段 (LS-II) 开始的影响.
主要方法:
- 使用了一种结合随机和非随机研究设计.
- 参与者在分娩后48小时内接受DMPA,安慰剂或没有注射.
- 倾向性得分权重被用于调整共变量.
主要成果:
- 在DMPA和对照组之间,LS-II的平均时间没有显著差异.
- 倾向性得分加权显示,DMPA组的LS-II发病时间平均差异为5.5小时较短 (95% CI,-16.4,5.5).
- 没有发现DMPA抑制LS-II发作的证据.
结论:
- 产后立即开始使用DMPA并不能抑制乳糖生成II阶段的开始.
- 研究结果支持DMPA在计划母乳养的个体中使用.
- 使用DMPA的早期产后避孕是母乳养母亲的可行选择.
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