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Updated: Jun 10, 2025

Dual CRISPR-Interference Strategy for Targeting Synthetic Lethal Interactions Between Non-Coding RNAs in Cancer Cells
07:23

Dual CRISPR-Interference Strategy for Targeting Synthetic Lethal Interactions Between Non-Coding RNAs in Cancer Cells

Published on: May 30, 2025

155

LncRNAs和癌症表观基因组:机制和治疗潜力

Revathy Nadhan1, Ciro Isidoro2, Yong Sang Song3

  • 1Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.

Cancer letters
|October 18, 2024
PubMed
概括

长非编码RNAs (lncRNAs) 是癌症中的关键表观遗传调节剂. 本综述探讨了它们在瘤进展中的作用和精密癌症医学的治疗潜力.

关键词:
癌症表观遗传学 癌症表观遗传学染色体重塑 染色体重塑 的方法通过DNA甲基化.表观遗传疗法是一种表观遗传疗法.基因组胺基因的修改长非编码RNAs (lncRNAs) 是一种长非编码RNA.瘤基因是一种瘤基因.精确瘤学是一门精确的专业.RNA干扰 (RNAi) 是一种RNA干扰.瘤抑制剂 瘤抑制剂

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