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Updated: Jun 10, 2025

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA
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对非添加性等位基因效应的全基因组搜索确定了PSKH2作为参与因子V活动的可变性

Blandine Gendre1, Angel Martinez-Perez2,3, Marcus E Kleber4,5

  • 1INSERM, Bordeaux Population Health Research Center, UMR 1219, ELEANOR, University of Bordeaux Bordeaux France.

Journal of the American Heart Association
|October 18, 2024
PubMed
概括

一个新型基因PSKH2通过影响其变异而不是平均水平,显著影响V因子 (FV) 血水平. 这一发现突显了中性粒细胞在FV调节中的作用,并确定了影响凝血的新遗传因素.

关键词:
布朗-福西斯试验 布朗-福西斯试验凝血是凝固的过程.血中的V因子水平.非添加物遗传影响的基因效应.母公司原产地效应.

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