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持续的梅毒眼部表现,尽管治疗:一个案例系列
Sairi Zhang1, Kaersti L Rickels1, Vignesh Krishnan1
1College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Journal of ophthalmic inflammation and infection
|October 18, 2024
概括
持续的眼球梅毒需要谨慎管理. 确保完整的青素治疗和下降的RPR标位进行有效的管理,然后如果需要,进行抗炎治疗以恢复视力.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 青素是梅毒治疗的黄金标准.
- 眼球梅毒会导致持续的后部部位炎症和视力丧失.
- 这个案例系列检查了持续的梅毒眼睛表现.
研究的目的:
- 描述三个持续性眼球梅毒病例.
- 突出处理耐治疗病例的挑战.
- 为管理持续性梅毒眼部表现提供建议.
主要方法:
- 三名患有持续性眼球梅毒的患者接受了静脉注射青素和口服普雷尼松的治疗.
- 病例1涉及梅毒性外视网膜病变 (SOR),乳头炎和急性梅毒性后部斑块性胆视网膜病变 (ASPPC) 与持续的囊性黄斑胀 (CME).
- 病例2和3涉及持续的SOR,ASPPC和乳头炎,其中一名患者再次感染.
主要成果:
- 持续的囊性黄斑 (CME) 在案例1中需要静脉内三氨和凯托洛拉克滴.
- 在案例2中,不完全的青素治疗导致了持续的SOR,需要用多西环素和普雷尼松重新治疗.
- 病例3显示了复发的ASPPC和持续的乳头炎,需要重新治疗以避免再次感染.
结论:
- 完整的青素治疗和下降的RPR标位对于管理持续性眼球梅毒至关重要.
- 在确保足够的治疗后,建议在持续的眼睛炎症中进行抗炎疗法.
- 延迟治疗,初始视力不佳,黄斑胀和艾滋病毒共感染等因素会使视觉预后恶化.
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