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Updated: Jun 10, 2025

Investigation of Macrophage Polarization Using Bone Marrow Derived Macrophages
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葡萄糖皮质体和IL4驱动的巨细胞编程之间的表观基因组和功能融合机制

Dinesh K Deochand1,2, Marija Dacic1,3, Michael J Bale4,5

  • 1Hospital for Special Surgery Research Institute, David Z. Rosensweig Genomics Center, New York, NY, USA.

Nature communications
|October 18, 2024
PubMed
概括

不同的信号汇聚在巨细胞编程上. 干白素-4和葡萄皮质激素诱导类似的组织修复状态,通过调节基因表达通过KLF4和葡萄皮质激素受体,集成GRIP1.

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