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Updated: Jun 10, 2025

An Adipocyte Cell Culture Model to Study the Impact of Protein and Micro-RNA Modulation on Adipocyte Function
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在肥胖症中,Sirtuin 1通过Ido1通路调节树突细胞的表型和功能

Jean de Lima1, Jefferson Antônio Leite1, Paulo José Basso1

  • 1Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.

Cell death & disease
|October 18, 2024
PubMed
概括

肥胖症中的Sirtuin 1 (SIRT1) 缺乏会损害树突细胞 (DC) 功能,并促进炎症. 减少的SIRT1影响DC代谢和kynurenine通路,驱动促炎性T细胞反应.

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