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Updated: Jun 10, 2025

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人类aquaporin-1中保存的H键网络对于本地折叠和寡合化是必要的

Philip Drewniak1, Peng Xiao1, Vladimir Ladizhansky1

  • 1Department of Physics and Biophysics Interdepartmental Group, University of Guelph, Guelph, ON, Canada.

Biophysical journal
|October 19, 2024
PubMed
概括

通过特定突变破坏人类水素素-1 (hAQP1) 中的键,导致蛋白质错折和四重体结构的丧失. 这些发现强调了结网络在维持AQP1稳定性和寡合化中的关键作用.

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