通过在线流色谱-LC-MS/MS在不同的矩阵中同时分析几个塑化剂类别
Julio Fernández-Arribas1, Sandra Callejas-Martos2, Aleix Balasch2
1Institute of Environmental Assessment and Water Research (IDAEA)-CSIC, Jordi Girona 18-26, 08034, Barcelona, Spain. jfaqam@cid.csic.es.
Analytical and bioanalytical chemistry
|October 19, 2024
概括
一种新的分析方法可以检测食物,口罩和空气中的多种塑化剂. 这项研究对于了解塑化剂对人类健康和环境的影响至关重要.
科学领域:
- 环境化学环境化学
- 分析化学 分析化学
- 毒理学 毒理学 毒理学
背景情况:
- 塑化剂在塑料制品中被广泛使用,引发了人们对其环境持久性和人类健康影响的担忧.
- 评估塑化剂的影响需要针对不同矩阵的强有力的分析方法.
- 现有的方法往往缺乏范围或效率,无法同时分析广泛的塑化剂.
研究的目的:
- 开发和验证用于确定多重塑化剂的快速分析方法.
- 分析食品中的增塑剂,面膜和室内空气样本.
- 评估不同类型的塑化剂对整体污染的贡献.
主要方法:
- 流色谱学 (TFC) 与双重质谱学 (MS-MS) 结合,用于在线净化和分析.
- 同时测定十种酸盐,四种替代性增塑剂 (酸盐,酸盐) 和20种有机酸盐 (OPEs).
- 在各种矩阵中验证方法,包括食品,面罩和环境空气.
主要成果:
- 在所有分析的样本中检测到可塑剂,其度在食品中高达22.0μg g−1 ww,在面膜中高达6.78μg g−1 和室内空气中高达572 ng m−3.
- 获得了可接受的分析参数,包括恢复率 (50125%) 和RSD (<20%).
- 酸盐,替代性增塑剂和OPE在矩阵中对总增塑剂含量有不同的贡献.
结论:
- 开发的TFC-MS-MS方法使得广泛的塑化剂能够同时进行高效的分析.
- 在食品,口罩和空气中存在塑化剂,强调需要进行全面的暴露评估.
- 这种方法对于获得关于可塑化剂从各种暴露来源对环境和人类健康的影响的确见解至关重要.
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