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介绍和管理患有上腺质量的患者:一个大型三级中心的经验
Onnicha Suntornlohanakul1,2, Sumedha Mandal3, Pratyusha Saha3
1Department of Metabolism and Systems Science, College of Medicine and Health, University of Birmingham, Birmingham B152TT, United Kingdom.
European journal of endocrinology
|October 19, 2024
概括
2016年关于上腺瘤的欧洲指南减少了不必要的手术,并增加了对良性上腺瘤的患者出院率. 这改善了临床实践,并保存了医疗保健资源.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 放射学 放射学是指放射学
背景情况:
- 上腺质很常见,影响5%-7%的成年人.
- 2016年欧洲指南旨在标准化上腺瘤管理.
- 此前,缺乏关于指南对临床实践的影响的证据.
研究的目的:
- 评估2016年欧洲指南对上腺瘤管理的影响.
- 在指南实施后,评估临床实践的变化,包括手术率和患者出院率.
主要方法:
- 对1397名患有上腺质量的患者 (1998-2022) 的回顾性审查.
- 对临床表现,放射学特征和诊断的分析.
- 部分分析比较2016年准则之前和之后的结果.
主要成果:
- 恶性病变预测因素包括>20 HU或异质密度,雄激素过量,癌症监测检测,大小≥4厘米和男性性别.
- 在指南实施后,上腺切除术减少了 (6.1%至4.5%).
- 良性,非功能上腺体质量的排出率显著增加 (4.4%至25.3%).
结论:
- 2016年的指导方针对上腺意外瘤的临床实践产生了积极的影响.
- 实施导致对良性上腺体质量减少不必要的手术.
- 良性质群体的出院率提高可以节约医疗保健资源,减少患者负担.
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