相关实验视频

Updated: Jun 10, 2025

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides
11:04

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides

Published on: September 7, 2019

9.1K

和铜效应 粉样蛋白前体蛋白的机械细胞粘附特性

Alexander August1, Sabrina Hartmann2, Sandra Schilling1

  • 1Department of Human Biology and Human Genetics, RPTU Kaiserslautern-Landau, Erwin-Schrödinger-Str. 13, D-67663 Kaiserslautern, Germany.

Biological chemistry
|October 19, 2024
PubMed
概括

铜和离子对粉样蛋白前体蛋白 (APP) 的二分化和结构有不同的影响. 结合增加了APP二分化,改变了结构特征,可能会影响阿尔茨海默病 (AD) 中的突触可塑性.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.在CD光谱学中使用CD光谱.粉样蛋白前体蛋白质是粉样蛋白的前体.分化二元化是指二元化的过程.神经退行症的神经退行症扫描力光谱法扫描力光谱法

更多相关视频

Quantifying the Binding Interactions Between CuII and Peptide Residues in the Presence and Absence of Chromophores11:38

Quantifying the Binding Interactions Between CuII and Peptide Residues in the Presence and Absence of Chromophores

Published on: April 5, 2022

2.4K
Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR14:44

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

Published on: December 16, 2013

9.6K

相关概念视频

Amyloid Fibrils03:03

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining,...
9.3K