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Updated: Jun 10, 2025

Induction of Murine Intestinal Inflammation by Adoptive Transfer of Effector CD4+CD45RBhigh T Cells into Immunodeficient Mice
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Induction of Murine Intestinal Inflammation by Adoptive Transfer of Effector CD4+CD45RBhigh T Cells into Immunodeficient Mice

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通过激活JAK2/STAT3/SOCS3信号通路,TIPE2会加剧实验性结肠炎并破坏肠上皮质屏障的完整性

Lingli Zeng1, Yuping Wang1, Jiaxin Shen1

  • 1Endoscopy Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China; Endoscopy Center, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China.

Experimental cell research
|October 19, 2024
PubMed
概括

瘤亡因子α诱导蛋白2 (TIPE2) 通过破坏肠道屏障,使性结肠炎 (UC) 恶化. 抑制TIPE2可能通过恢复屏障功能和减少炎症,为UC提供治疗策略.

关键词:
实验性结肠炎是一种实验性结肠炎.肠道上皮质屏障 肠道上皮质屏障在 JAK2/STAT3/SOCS3 信号通路中.类型2 类型2 类型2

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Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis08:58

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