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Updated: Jun 10, 2025

A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds
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A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds

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对瘤生长抑制模型的概率分析,以支持试验设计

Marcus Baaz1, Tim Cardilin2, Torbjörn Lundh3

  • 1Fraunhofer-Chalmers Research Centre for Industrial Mathematics, Gothenburg, Sweden; Department of Mathematical Sciences, Chalmers University of Technology and University of Gothenburg, Gothenburg, Sweden.

Journal of theoretical biology
|October 19, 2024
PubMed
概括

确定临床试验的最佳患者样本大小至关重要. 本研究引入了一种新的参数模型,使用瘤生长抑制和RECIST标准来计算样本大小,平衡统计学意义与临床相关性和成本效益.

关键词:
组合疗法是一种组合疗法.数学建模的数学建模非线性混合效应非线性混合效应在瘤学瘤学.权力分析 权力分析

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Multiplexed Immunofluorescence Analysis and Quantification of Intratumoral PD-1+ Tim-3+ CD8+ T Cells09:32

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