减肥,身体组成的变化和炎症状况在非常低能量的类疗法 (VLEKT) 后:性别是否重要?
Giovanna Muscogiuri1,2,3, Ludovica Verde2,4, Evelyn Frias-Toral5
1Diabetologia e Andrologia, Dipartimento di Medicina Clinica e Chirurgia, Unità di Endocrinologia, Università Degli Studi di Napoli Federico II, Via Sergio Pansini 5, 80131, Naples, Italy.
Journal of translational medicine
|October 19, 2024
概括
与女性相比,男性在45天的肥胖非常低能量的热疗法 (VLEKT) 中体重减轻和炎症标志物减少. 这些发现强调了在个性化体重管理策略中需要针对性别的方法.
科学领域:
- 代谢健康 代谢健康
- 肥胖问题研究研究
- 营养科学 营养科学
背景情况:
- 肥胖在性别之间在身体组成和炎症方面提出了独特的挑战.
- 个性化饮食策略越来越多地被推用于有效的肥胖管理.
- 了解性别特异性对干预措施的反应对于定制治疗至关重要.
研究的目的:
- 为了研究性别对减肥,身体组成变化和炎症状况的影响.
- 为了比较经过非常低能量的热疗法 (VLEKT) 的绝经前女性和男性之间的结果.
- 评估VLEKT在1级和2级肥胖患者的疗效,同时考虑性别差异.
主要方法:
- 参与者接受了为期45天的非常低能量的性疗法 (VLEKT) 干预.
- 评估了人体测量测量 (体重,BMI,腰围) 和身体组成.
- 使用高灵敏性C反应蛋白 (hs-CRP) 水平测量炎症状态干预前和后.
主要成果:
- 与女性相比,男性的体重减轻 (11.63%与8.95%) 和脂肪量减少 (30.84%与21.36%) 显著增加.
- 男性的hs-CRP水平下降幅度比女性更大 (41.42%对22.38%).
- 阶段角值,表明细胞膜完整性,在男性 (17.11%与7.05%) 比女性更显著地改善.
结论:
- 性别显著影响着VLEKT在肥胖个体中的有效性.
- 男人似乎从VLEKT中获得了更大的好处,包括减肥,身体组成和炎症.
- 这些结果强调,在个性化肥胖治疗计划中,包括饮食干预措施,必须考虑性别特异性考虑.
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