饮食限制,社会经济因素,获得脏移植,等待名单死亡率等等待名单死亡率等等
Emily A Johnston1, Jingyao Hong2, Akanksha Nalatwad2
1Department of Medicine, New York University Grossman School of Medicine and Langone Health, New York, New York, USA.
Clinical transplantation
|October 20, 2024
概括
饮食限制显著影响移植清单和存活率. 极度受饮食规则困扰的患者在粮食不安全的社区面临更低的移植名单机会和更高的等待名单死亡率.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 移植医学 移植医学
- 公共卫生 公共卫生
背景情况:
- 饮食限制对末期脏病 (ESKD) 患者来说是一个很大的负担.
- 这种负担可能会阻碍缺乏社区资源的候选人获得移植 (KT).
研究的目的:
- 调查饮食限制的感知负担与移植 (KT) 结果之间的关联.
- 确定邻里社会经济因素是否会改变这些关联.
主要方法:
- 一项针对2471名ESKD患者的前性队列研究,从2014-2023年对KT进行评估.
- 评估饮食限制和社区社会经济因素 (例如,粮食不安全) 的感知负担.
- 使用Cox和竞争风险模型来分析与KT上市和等待名单死亡率的关联.
主要成果:
- 18%的KT候选人报告说,饮食限制给他们带来了极大的麻烦.
- 极端的烦与KT上市的可能性较低有关 (aHR=0.75).
- 在高粮食不安全社区的极度困扰候选人中观察到更高的等候名单死亡率 (aSHR=2.07).
结论:
- 对饮食限制的感知负担会对KT上市产生负面影响.
- 由于饮食负担增加的等候名单死亡率是高粮食不安全地区的候选人的特点.
- 移植中心应该以营养支持和粮食援助为目标,针对弱势患者.
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