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儿童不良经历和左海马体体积减小:一个结构磁共振成像研究

Ashlyn Schwartz¹, Mélissa Macalli², Marie C Navarro²

¹Trinity College, Department of Public Health & Primary Care, D24 DH74, Dublin, Ireland.

Journal of psychiatric research

|October 20, 2024

概括

童年不良经历 (ACE) 与年轻成年人的海马体积减少有关. 这项研究发现,在学生样本中,增加ACEs暴露与较小的左和右海马体积相关.

科学领域:

神经科学是一个神经科学.
心理学心理学心理学
公共卫生公共卫生

背景情况:

儿童不良经历 (ACE) 与成年人的大脑结构变化有关.
以前的研究集中在特定的ACE上,样本大小小小.
在一般人群中,对ACE对年轻成年人大脑结构的影响的研究是有限的.

研究的目的:

基于年轻成年人ACE暴露的海马体积差异的研究.
在学生样本中调查ACE暴露与左/右海马体积之间的关联.

主要方法:

959名大学生 (18-24岁) 完成了关于ACE,心理健康和人口统计的在线问卷.
磁共振成像 (MRI) 测量了左和右海马体积.
线性回归分析了与ACE暴露相关的海马体积差异.

主要成果:

65.9%的学生报告了ACEs的暴露.
增加的ACE暴露与左侧和右侧海马体和杏仁体量显著减少相关.
在调整后,较高的ACE暴露与左海马体积减少有关 (p=0.0412).

结论:

年轻成人学生的海马体积与ACE暴露有关.
ACEs有助于与普通人群相比,年轻成年人的神经解剖学差异.

关键词:

不良的童年经历儿童的不良经历新兴成年期的成年人.河马体积的体积是什么结构磁共振成像技术结构磁共振成像技术大学的学生大学生.基于体积的形态测量.

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