受到约束的内 (在145°内置植入物中) 有没有任何好处? 一个匹配的回顾性研究
Samuel Lorentz1, Caroline N Park1, Christopher P Roche2
1Department of Orthopaedic Surgery, Duke University, Durham, NC, USA.
Journal of shoulder and elbow surgery
|October 20, 2024
概括
在逆向全肩关节整形术 (rTSA) 中,受约束的带与标准带相比,没有显著改善疼痛或运动范围. 然而,受约束的内与更高的不良事件发生率有关,包括肩膀刺.
科学领域:
- 整形外科手术 整形外科手术
- 生物医学工程 生物医学工程
- 肌肉骨研究的研究.
背景情况:
- 反向全肩关节整形手术 (rTSA) 是肩关节功能障碍的一种常见手术.
- 约束是RTSA中使用的一种修改,但它们的临床益处仍在争论中.
- 了解与受约束线相关的结果对于手术决策至关重要.
研究的目的:
- 为了比较使用受约束和标准的初级RTSA的临床结果.
- 为了评估疼痛,运动范围,患者报告的结果和并发症的差异,在至少1年的随访中.
主要方法:
- 一项对836名初级RTSA患者的回顾性分析.
- 209名受约束线患者与1:3的627名标准线患者进行了交叉匹配.
- 记录和分析了包括疼痛,运动范围 (ROM),患者报告的结果 (PRO),并发症和修订在内的结果.
主要成果:
- 在两组之间疼痛,绑架,向前升高,内部/外部旋转,ASES分数或SAS分数的改善方面没有发现统计学上显著的差异.
- 受到约束的线性队列表现出明显更高的不良事件率 (6.2%对2.7%),特别是肩膀 (15.6%对8.8%).
结论:
- 在1年的随访中,带有受约束的初级RTSA在缓解疼痛或改善功能方面与标准相比没有显著的优势.
- 狭窄的内与更高的不良事件发生率有关,特别是头上的痕.
- 需要进行进一步的长期研究,以确定在RTSA中受约束的整体疗效和耐用性.
相关概念视频
Internal Receptors
Many cellular signals are hydrophilic and therefore cannot pass through the plasma membrane. However, small or hydrophobic signaling molecules can cross the hydrophobic core of the plasma membrane and bind to internal, or intracellular, receptors that reside within the cell. Many mammalian steroid hormones use this mechanism of cell signaling, as does nitric oxide (NO) gas.
Structure of Conjugated Dienes
Introduction
Conjugated dienes are compounds characterized by the presence of alternating double and single bonds. In a conjugated system like 1,3-butadiene, the unhybridized 2p orbital on each carbon overlaps continuously, allowing the π electrons to be delocalized across the entire molecule. In contrast, this type of overlap does not occur in cumulated and isolated dienes, such as 2,3-pentadiene and 1,4-pentadiene, respectively. Instead, the π electrons remain localized between the double...
Conjugated dienes are compounds characterized by the presence of alternating double and single bonds. In a conjugated system like 1,3-butadiene, the unhybridized 2p orbital on each carbon overlaps continuously, allowing the π electrons to be delocalized across the entire molecule. In contrast, this type of overlap does not occur in cumulated and isolated dienes, such as 2,3-pentadiene and 1,4-pentadiene, respectively. Instead, the π electrons remain localized between the double...
Stability of Conjugated Dienes
Introduction
A comparison of the enthalpies of hydrogenation of dienes reveals that conjugated dienes release less heat on hydrogenation, rendering them more stable than their nonconjugated analogs.
A comparison of the enthalpies of hydrogenation of dienes reveals that conjugated dienes release less heat on hydrogenation, rendering them more stable than their nonconjugated analogs.
Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)
Two NMR-active nuclei bonded to a central atom can be involved in geminal or two-bond coupling. Geminal coupling is commonly seen between diastereotopic protons in chiral molecules and unsymmetrical alkenes, among others.
The central atom need not be NMR-active because its electrons are affected by the electron polarization of the spin-active atoms. However, spin information is transmitted less effectively than in one-bond coupling, and 2J values are usually weaker than 1J values. The energy of...
The central atom need not be NMR-active because its electrons are affected by the electron polarization of the spin-active atoms. However, spin information is transmitted less effectively than in one-bond coupling, and 2J values are usually weaker than 1J values. The energy of...
Mismatch Repair
Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
Symmetric Member in Bending
In the study of the mechanics of materials, analyzing the behavior of prismatic members under opposing couples is crucial for understanding internal stress distributions, which are essential for structural design. When subjected to couples, a prismatic member experiences internal forces that maintain equilibrium. A couple, characterized by two equal and opposite forces, creates a moment but no resultant force. The internal forces at any section cut of the member must balance these external...


