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儿童急性传染性结膜炎的病因和结果
Holly M Frost1, Timothy C Jenkins2, Jennifer C Meece3
1Center for Health Systems Research, Denver Health and Hospital Authority, Denver, CO; Department of Pediatrics, Denver Health and Hospital Authority, Denver, CO; Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO.
The Journal of pediatrics
|October 20, 2024
概括
海莫菲勒斯流感是唯一与儿童结膜炎有显著联系的细菌. 大多数病例在五天内消失,但抗生素副作用很常见,强调需要谨慎处方.
科学领域:
- 眼科医生 眼科 眼科
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
背景情况:
- 结膜炎是一种常见的儿童疾病,有各种原因.
- 了解病原体特异性表现和结果对于有效治疗至关重要.
研究的目的:
- 为了确定儿童结膜炎的致病原体.
- 为了确定临床特征和康复率是否因病原体而异.
主要方法:
- 一项多中心病例控制研究,涉及390名儿童 (194例,196例对照).
- 用聚合酶链反应 (PCR) 分析细菌和病毒病原体的结膜样本.
- 护理人员调查收集了有关症状,抗生素使用,缺学和不良事件的数据.
主要成果:
- 血型流感是唯一与结膜炎显著相关的病原体 (aOR 4.59).
- 在H. influenzae病例中,性分泌物更常见 (aOR 2.47).
- 大多数儿童 (96%) 在第五天得到改善,不管他们是否服用了抗生素;然而,在接受局部抗生素治疗的儿童中,有20%报告了不良事件.
结论:
- H. influenzae 是儿童结膜炎的主要细菌原因.
- 到第五天的临床表现和解决方案在检测到的病原体中是相似的.
- 谨慎的抗生素处方是必不可少的,因为在20%的治疗儿童中报告了不良事件.
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