美国的门诊婴儿肉毒瘤,1976-2021年
Jessica M Khouri1, Haydee A Dabritz1, Jessica R Payne1
1Infant Botulism Treatment and Prevention Program, Infectious Diseases Laboratories Division, Center for Laboratory Sciences, California Department of Public Health, Richmond, CA.
The Journal of pediatrics
|October 20, 2024
概括
门诊婴儿肉毒症 (IB) 很少见,但在全国范围内发生,经常出现便秘和神经等轻微症状,使得诊断具有挑战性. 提高医疗保健提供者的意识对于在婴儿中识别这些不那么严重的IB病例至关重要.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 神经学 神经学
背景情况:
- 婴儿肉毒症 (IB) 是一种罕见但严重的疾病,由 *Clostridium botulinum* 毒素引起.
- 大多数IB病例需要住院治疗,但在门诊患者中可能出现较轻的形式.
研究的目的:
- 描述美国婴儿肉毒症 (IB) 的门诊病例.
- 了解非住院IB婴儿的临床表现和诊断挑战.
主要方法:
- 从婴儿肉毒症治疗和预防计划 (1976-2021) 的数据分析.
- 门诊IB病例的定义是那些具有临床症状和实验室确认,不需要住院治疗的IB病例.
主要成果:
- 在45年内,只有17例 (0.4%) 的门诊IB病例被确定.
- 便秘 (94%) 和神经 (94%) 是最常见的症状.
- 病例发生在全国范围内,发病时平均年龄为20周.
结论:
- 门诊IB可能由于轻微而不需要住院治疗的症状而未得到充分认可.
- 诊断需要临床怀疑和实验室确认.
- 医疗保健提供者应该考虑IB在婴儿失败壮成长,食问题,便秘,或神经.
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