阿片类药物使用障碍对喘住院的影响:一项倾向匹配的全国性研究
Francisco J Gallegos-Koyner1, Franc Hodo1, Nelson I Barrera1
1St. Barnabas Hospital Health System, Department of Internal Medicine, City University of New York School of Medicine, Bronx, New York.
概括
阿片类药物使用障碍 (OUD) 不会增加喘住院的死亡率. 然而,患有喘和OUD的患者面临更糟糕的二次结果,包括更高的机械呼吸率和更长的住院时间.
科学领域:
- 肺部医学 肺部医学
- 成 药物 药物 药物 药物
- 医疗保健服务研究 医疗服务研究
背景情况:
- 患有喘和阿片类药物使用障碍 (OUD) 的患者面临更高的急性恶化率.
- OUD对喘相关住院病人的影响仍未得到充分研究.
研究的目的:
- 调查与OUD同时使用的成年喘患者的临床结果.
- 为了比较患有OUD和没有OUD的喘患者之间的住院结果.
主要方法:
- 利用国家住院患者样本来识别具有和没有OUD的成年喘患者.
- 雇佣了1:1的倾向分数匹配,以创建可比的队列.
- 专注于住院死亡率作为主要结局.
主要成果:
- 患有OUD和没有OUD的喘患者在住院死亡率上没有显著差异.
- 患有OUD的喘患者经历了更高的机械呼吸和非侵入性呼吸率.
- 患有OUD的患者在住院的平均时间明显长.
结论:
- 同时使用OUD并不会增加喘住院患者的死亡风险.
- 患有OUD的喘患者表现出较差的二次结果,包括增加对呼吸系统支持的需求和延长住院时间.
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