在慢性失眠障碍的情绪干扰下,在认知控制期间减少前额外激活
Sun-Young Kim1, Kyung Hwa Lee2,3, Jeong Eun Jeon3
1Department of Psychiatry, Ewha Womans University College of Medicine, Ewha Womans University Seoul Hospital, Seoul, Republic of Korea.
Journal of sleep research
|October 20, 2024
概括
患有慢性失眠障碍的患者在处理负面情绪刺激时,右前额前皮层的神经激活减少. 这种神经差异与睡眠质量降低和睡眠障碍增加有关.
科学领域:
- 神经科学是一个神经科学.
- 睡眠医学 睡眠医学
- 认知心理学 认知心理学
背景情况:
- 慢性失眠症与认知和情绪失调有关.
- 了解失眠的认知控制缺陷的神经基础对于开发有针对性的干预措施至关重要.
研究的目的:
- 为了研究慢性失眠障碍患者在认知控制任务期间神经激活的改变.
- 检查神经激活模式,情绪干扰和主观睡眠障碍之间的关系.
主要方法:
- 功能性磁共振成像 (fMRI) 用于评估在48名患有慢性失眠障碍的患者和48名对照者的情绪Stroop任务期间的大脑活动.
- 参与者填写了关于睡眠质量和情绪困扰的验证问卷,以及睡眠日记.
主要成果:
- 与对照组相比,患有慢性失眠障碍的患者在暴露于负面情绪词语时,表现出右前额前皮质神经活化减少.
- 这种减少的激活与失眠严重程度得分 (例如,匹兹堡睡眠质量指数,失眠严重程度指数) 有负相关性,与自我报告的睡眠效率和总睡眠时间有正相关性.
结论:
- 在失眠患者中,右前额前皮层活动的减少表明,对负面情绪刺激的上下抑制受损.
- 这种神经缺陷可能会导致认知性过度兴奋,反和慢性失眠障碍特征的主观睡眠障碍.
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