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Updated: Jun 10, 2025

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
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Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach

Published on: June 10, 2021

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罗利兹维林,一种独特的细菌类化合物,由非核糖体合成酶和非酶体二分化组装在一起

Juliana Effert1, Margaretha Westphalen2, Andrea Calderari3

  • 1Max Planck Institute for Terrestrial Microbiology, Department of Natural Products in Organismic Interactions, 35043, Marburg, Germany.

Angewandte Chemie (International ed. in English)
|October 20, 2024
PubMed
概括

这项研究通过识别Xenorhabdus hominickii中的新型基因集群,阐明了pyrrolizidine类化合物 (PAs) 的细菌生物合成,特别是伪二次体pyrrolizwilline. 研究人员详细介绍了该途径并描述了关键酶的特征,进步了我们对复杂细菌PA生产的理解.

关键词:
在X射线晶体学.细菌天然产品是一种细菌天然产品.生物合成生物合成罗利齐丁类类化合物一个αβ酸酶.

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