在接受癌症化学放射治疗的住院患者中预测癌症相关静脉血栓栓塞的诺莫图
Yan Sisi1, Li Genpeng2, Chen Yao1
1Radiation Oncology Center, Chongqing University Cancer Hospital, Chongqing, China.
Cancer control : journal of the Moffitt Cancer Center
|October 21, 2024
概括
一种新型的诺姆图有效预测癌症相关静脉血栓栓塞 (CAT) 在接受化疗或放射治疗的住院癌症患者中. 该工具有助于评估不良结果的风险,以改善临床管理.
科学领域:
- 在瘤学瘤学.
- 血液学 血液学 血液学
- 医疗信息学 医疗信息学
背景情况:
- 与癌症相关的静脉血栓塞栓症 (CAT) 对接受化疗或放射治疗的患者构成重大风险.
- 准确预测CAT对于及时干预和改善患者结果至关重要.
研究的目的:
- 开发和验证一种用于预测住院癌症患者接受化疗和放射治疗的CAT的新型名谱.
主要方法:
- 在2010年至2022年期间接受治疗的778名患者的回顾性队列研究.
- 后勤回归确定了风险因素;构建了一个名图并进行了内部验证.
- 使用ROC,校准曲线和DCA评估的性能.
主要成果:
- 纳米图包括年龄,癌症阶段,NSAID使用,D-二次体和糖尿病史.
- AUC值为0.816 (培训) 和0.781 (验证),表明预测准确度很好.
- 诺米图表显示了良好的校准和临床适用性.
结论:
- 在这种患者群体中,CAT发病率很高.
- 开发的名图是预测CAT风险的有效工具.
- 该模型为管理化疗放射治疗患者提供了有价值的临床参考.
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