维生素D缺乏与前庭功能的关联,在患有异常良性性定位的患者中
Tao Lin1, Changzhen Wu2, Luguang Zhang3
1Department of Neurosurgery, Shandong Second Provincial General Hospital, Jinan, China.
The Journal of laryngology and otology
|October 21, 2024
概括
维生素D缺乏与良性发性位置性 (BPPV) 患者的前庭功能异常有关. 低维生素D水平也预测了BPPV的复发,强调了它在管理这种疾病中的重要性.
科学领域:
- 神经学 神经学
- 内分泌学 在内分泌学.
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 良性发性位置性 (BPPV) 是导致头的常见原因.
- 静脉功能障碍和复发是BPPV管理中的重大挑战.
- 维生素D在BPPV病理生理学中的作用仍在研究中.
研究的目的:
- 检查BPPV患者维生素D水平与前庭功能之间的关联.
- 为了确定维生素D缺乏是否会影响BPPV的复发率.
主要方法:
- 招募了138名BPPV患者.
- 使用热量测试,宫前置唤起肌原潜力 (cVEMPs) 和眼睛前置唤起肌原潜力 (oVEMPs) 来评估前置功能.
- 测量了血清维生素D水平,并与前体检测结果和复发数据相关联.
主要成果:
- 患有前庭功能异常的患者 (热量,cVEMP,oVEMP测试) 的维生素D水平显著降低.
- 正常的维生素D水平与前庭功能异常的可能性较低有关.
- 维生素D水平被确定为BPPV复发的唯一预测因素.
结论:
- 维生素D缺乏与BPPV的前体异常有关.
- 这些前庭功能障碍,可能受到维生素D状态的影响,可能会导致BPPV复发.
- 维持足够的维生素D水平可能对改善前庭功能和减少BPPV复发至关重要.
相关概念视频
Equilibrium and Balance
4.5K
The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...
4.5K
Role of Vitamins in Maintaining Bone Health
3.2K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
3.2K
Bone Disorders
3.4K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.4K
Vitamins
573
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
573
Alterations in Blood Pressure
1.2K
Alterations in blood pressure, such as hypertension (high blood pressure) and hypotension (low blood pressure), significantly affect human health. Understanding these conditions' classifications, causes, and symptoms is essential for effective management and treatment.
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...
1.2K
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
2
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
2


