一个3D快速MR弹性图序列与间接的多叶片采集和哈达马德编码
Runke Wang1,2,3, Yu Chen1,2,3, Fuhua Yan4,5
1School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Magnetic resonance in medicine
|October 21, 2024
概括
使用DENSE成像的新的快速MR弹性图像 (MRE) 序列可以显著加快扫描时间,而不会导致扭曲工件. 这一进步增强了MRI功能能力,用于准确的刚度测量.
科学领域:
- 磁共振成像技术 磁共振成像技术
- 生物医学工程 生物医学工程
- 医学物理 医学物理
背景情况:
- 磁共振弹性图 (MRE) 对于评估组织硬度至关重要.
- 现有的MRE技术在获取速度和潜在的扭曲工件方面存在局限性.
- 提高MRE的功能能力需要更快的成像,而不会影响准确性.
研究的目的:
- 为快速获取数据开发一种新的MRE序列.
- 为了实现高速的MRE成像,而不会引入扭曲器件.
- 为了提高MRI在弹性图应用中的整体功能能力.
主要方法:
- 使用了带有多相获取的位移编码刺激回声 (DENSE) 序列.
- 实施了中心外黄金角星采样,以改善SNR.
- 为了提高效率,采用了哈达马德编码和间接的多块板获取.
- 应用并行成像和压缩传感用于加速采集.
主要成果:
- 与GRE MRE相比,实现了6倍的加速,与PI/CS相比,进一步加速了8倍.
- 在不同序列中证明了最小的刚度测量变异 (<9.23%).
- 与基于EPI的序列相比,报告了较高的对比度与噪声比率 (1.38).
- 在脑成像中验证了准确的硬度估计和文物避免.
结论:
- 开发了一个基于DENSE的快速MRE序列.
- 实现了与基于EPI的序列可比的获取速度.
- 保持了信号噪声比 (SNR) 和避免了扭曲器件.
相关概念视频
01:17NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences
A pulse is a short burst of radio waves distributed over a range of frequencies that simultaneously excites all the nuclei in the sample. Upon passing a radio frequency pulse along the x-axis, the nuclei absorb energy corresponding to their Larmor frequencies and achieve resonance. This shifts the net magnetization vector from the z-axis toward the transverse plane. This angle of rotation of the magnetization vector, or the flip angle, is proportional to the duration and intensity of the pulse.
01:07Electron Microscope Tomography and Single-particle Reconstruction
Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...