症状与无症状心房的主要临床结果:元分析
Paschalis Karakasis1, Konstantinos Pamporis2, Konstantinos C Siontis3
1Second Department of Cardiology, Aristotle University of Thessaloniki, Hippokration General Hospital, Thessaloniki, Greece.
European heart journal
|October 21, 2024
概括
在心房患者的症状状态没有显著影响主要的临床结果,如中风或死亡率. 然而,无症状的个体显示出进展到永久性AF的风险更高.
科学领域:
- 心脏病学 心脏病学
- 临床结果研究研究
- 在心房的管理管理.
背景情况:
- 目前的指导方针将无症状心房动 (AF) 与比症状心房动更高的中风和死亡风险联系在一起.
- 最近的相互矛盾的证据需要重新评估AF患者的症状状况和临床结果.
研究的目的:
- 评估被诊断患有心房动的患者的症状状况和临床结果之间的关联.
- 为了澄清症状与无症状心房动的预后影响.
主要方法:
- 在Medline,Cochrane图书馆和Scopus数据库中进行了系统的文献搜索.
- 进行了三重独立的研究选择,数据提取和质量评估.
- 使用随机效应的元分析,从36项涉及217,850名参与者的研究中汇集了证据.
主要成果:
- 在症状和无症状的AF患者之间,没有发现所有原因死亡率,心血管死亡率,血栓栓塞,中风,住院或心肌梗塞风险的显著差异.
- 有症状的患者患上新发性心力衰竭的风险增加了33%,进展为永久性心力衰竭的风险降低了30%.
- 有症状的患者更有可能接受抗心律失常药物和废除疗法.
结论:
- 根据AF症状状态,主要的临床结果没有显著差异.
- 无症状心房的患者表现出更大的风险进展到永久的AF.
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