在发育中部低血压症中部问题的发生率:一个范围审查
Roslyn W Livingstone1, Ginny S Paleg2, M Wade Shrader3
1Occupational Science and Occupational Therapy, University of British Columbia, Vancouver, BC, Canada.
Developmental medicine and child neurology
|October 21, 2024
概括
发育中部低血压症的儿童面临部问题的风险增加. 早期的超声波和正在进行的骨科检查对于及时诊断和管理关节发育不良和部脱至关重要.
科学领域:
- 儿科整形外科 儿科整形外科
- 临床遗传学 临床遗传学
- 发育儿科 发育儿科
背景情况:
- 发育中心低血压是影响儿童肌肉度的疾病.
- 部问题,包括发育不良和脱,可在患有低血压的人群中出现.
- 罕见的遗传综合征通常与低血压相关,并且可能出现独特的部异常.
研究的目的:
- 审查和综合现有的关于发育性中央低血压症患者部问题的文献.
- 为了确定与部异常相关的特定遗传诊断.
- 了解这一群体中部问题的进展和风险因素.
主要方法:
- 在五个数据库中进行系统的文献搜索,截至2023年10月.
- 排除唐氏综合征,以关注不太常见的遗传诊断.
- 从79项符合条件的研究中,至少有两名审查员进行独立选和数据提取.
主要成果:
- 该审查包括544名患有罕见遗传综合征的个人,如卡布基,普拉德-威利和沃尔夫-希尔斯霍恩.
- 部结构上的差异,发育不良和脱是常见的,通常在婴儿期发展.
- 关节松,低血压和高移动性被确定为关键风险因素.
结论:
- 显著低血压的儿童有部问题的高风险,可能会被标准新生儿查遗漏.
- 建议在6周至6个月之间进行超声波查.
- 建议对老年儿童和患有持续性低血压症的成年人每年进行骨科检查,并定期进行放射检查.
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