进入第三级新生儿重症监护病房的新生儿的肠道营养在无otropic 支持上:一个前性队列研究
Deepika Mittapalli1, Anil K Sajjan1, Siddu Charki1
1Pediatrics, Shri B. M. Patil Medical College Hospital and Research Centre, BLDE (Deemed to be University), Vijayapura, IND.
Cureus
|October 21, 2024
概括
新生儿的早期肠道营养在无otropic 支持下显著减少新生儿重症监护室 (NICU) 的停留时间并改善结果. 上腺素和多布他胺在特定剂量是最佳的食耐受性在这些脆弱的婴儿.
科学领域:
- 新生儿科学 新生儿科学
- 儿科重症监护 儿科重症监护
- 临床营养学 临床营养学
背景情况:
- 在新生儿的早期肠道养中,以无otropic 支持为基础,可能比静脉注射液体提供更好的结果.
- 然而,对于启动肠道营养的安全性和最佳内水平尚不清楚.
研究的目的:
- 为了评估新生儿早期的肠道养与静脉注射液体,在无otropic 支持下.
- 为了比较临床结果,包括住院,发病率和死亡率.
- 评估安全性并确定最佳的内水平,以适应肠道营养的耐受性.
主要方法:
- 一项前性队列研究涉及142名新生儿,患有液体无反应冲击.
- 肠道营养组与静脉输液组之间的比较.
- 使用独立样本 t 测试,曼·惠特尼 U 测试,奇方位和费舍尔精确测试 (p <0.05 显著性) 的统计分析.
主要成果:
- 肠道营养组显示,与静脉注射液体组 (78.87%) 相比,新生儿改善和放出的比例更高 (87.32%).
- 在肠道营养组 (p<0.0001) 中,完全养的平均时间 (6.04天) 和新生儿重症监护室停留时间 (7.38天) 显著较短 (p<0.0001).
- 肠道营养组的死亡率较低 (8.45%) 与静脉注射液体组 (10.08%) 相比.
结论:
- 在新生儿中早期的肠道养与无otropic 支持相关,与显著更短的 NICU 停留时间有关,这表明改善了临床管理.
- 上腺素 (0.1 毫克克/公斤) 与多布他胺 (10 毫克克/公斤) 结合,被确定为肠道料耐受性的最佳内组合.
相关概念视频
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
83
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
83
Enteral Nutrition I: Orogastric and Nasogastric Feeding
207
Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
207
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
103
Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
103


